Z217-1214 Screening compound: 2-{methyl[3-methyl-1-(3-methylphenyl)-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]amino}-N-[(pyridin-3-yl)methyl]acetamide

Z217-1214 Screening compound: 2-{methyl[3-methyl-1-(3-methylphenyl)-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]amino}-N-[(pyridin-3-yl)methyl]acetamide
Z217-1214 Screening compound: 2-{methyl[3-methyl-1-(3-methylphenyl)-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]amino}-N-[(pyridin-3-yl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z217-1214
2-{methyl[3-methyl-1-(3-methylphenyl)-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]amino}-N-[(pyridin-3-yl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z217-1214

Molecular Formula

C21H22N6OS (C21 H22 N6 OS)

Compound Name

2-{methyl[3-methyl-1-(3-methylphenyl)-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]amino}-N-[(pyridin-3-yl)methyl]acetamide

IUPAC name

2-{methyl[3-methyl-1-(3-methylphenyl)-1H-pyrazolo[34-d][13]thiazol-5-yl]amino}-N-[(pyridin-3-yl)methyl]acetamide

SMILES

Cc(c1c2nc(N(C)CC(NCc3cnccc3)=O)s1)nn2-c1cc(C)ccc1

InChI

InChI=1S/C21H22N6OS/c1-14-6-4-8-17(10-14)27-20-19(15(2)25-27)29-21(24-20)26(3)13-18(28)23-12-16-7-5-9-22-11-16/h4-11H,12-13H2,1-3H3,(H,23,28)

InChI Key

AVFVCJKSUUTGDI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27634732

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.009

Distribution Coefficient, logD

3.006

Water Solubility, LogSw

-2.94

Polar Surface Area

61.783

Acid Dissociation Constant (pKa)

13.91

Base Dissociation Constant (pKb)

5.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

Z217-1214 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with Z217-1214 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z217-1214?
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What is the minimum amount of Z217-1214 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z217-1214
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z217-1214
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z217-1214 available by request