Z218-0085 Screening compound: N-[3-(1-ethyl-1H-indol-2-yl)-1H-pyrazol-5-yl]-3,5-dimethylbenzamide

Z218-0085 Screening compound: N-[3-(1-ethyl-1H-indol-2-yl)-1H-pyrazol-5-yl]-3,5-dimethylbenzamide
Z218-0085 Screening compound: N-[3-(1-ethyl-1H-indol-2-yl)-1H-pyrazol-5-yl]-3,5-dimethylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z218-0085
N-[3-(1-ethyl-1H-indol-2-yl)-1H-pyrazol-5-yl]-3,5-dimethylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z218-0085

Molecular Formula

C22H22N4O (C22 H22 N4 O)

Compound Name

N-[3-(1-ethyl-1H-indol-2-yl)-1H-pyrazol-5-yl]-3,5-dimethylbenzamide

IUPAC name

N-[3-(1-ethyl-1H-indol-2-yl)-1H-pyrazol-5-yl]-35-dimethylbenzamide

SMILES

CCn(c(-c1n[nH]c(NC(c2cc(C)cc(C)c2)=O)c1)c1)c2c1cccc2

InChI

InChI=1S/C22H22N4O/c1-4-26-19-8-6-5-7-16(19)12-20(26)18-13-21(25-24-18)23-22(27)17-10-14(2)9-15(3)11-17/h5-13H,4H2,1-3H3,(H2,23,24,25,27)

InChI Key

FJZKHBZFAJNCDA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27634848

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

358.44

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.984

Distribution Coefficient, logD

4.983

Water Solubility, LogSw

-5.13

Polar Surface Area

46.837

Acid Dissociation Constant (pKa)

10.93

Base Dissociation Constant (pKb)

-0.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

Z218-0085 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

C-Met Library (15277 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • Kinases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with Z218-0085 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z218-0085?
Check Price and Availability of Z218-0085, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z218-0085 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z218-0085
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z218-0085
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z218-0085 available by request