Z218-0779 Screening compound: N-[3-(1-ethyl-5-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]pyridine-3-carboxamide

Z218-0779 Screening compound: N-[3-(1-ethyl-5-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]pyridine-3-carboxamide
Z218-0779 Screening compound: N-[3-(1-ethyl-5-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z218-0779
N-[3-(1-ethyl-5-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z218-0779

Molecular Formula

C20H19N5O2 (C20 H19 N5 O2)

Compound Name

N-[3-(1-ethyl-5-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]pyridine-3-carboxamide

IUPAC name

N-[3-(1-ethyl-5-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]pyridine-3-carboxamide

SMILES

CCn(c(-c1n[nH]c(NC(c2cnccc2)=O)c1)c1)c(cc2)c1cc2OC

InChI

InChI=1S/C20H19N5O2/c1-3-25-17-7-6-15(27-2)9-14(17)10-18(25)16-11-19(24-23-16)22-20(26)13-5-4-8-21-12-13/h4-12H,3H2,1-2H3,(H2,22,23,24,26)

InChI Key

KSCFASFPLPILLF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27634906

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

361.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.979

Distribution Coefficient, logD

2.979

Water Solubility, LogSw

-3.13

Polar Surface Area

63.898

Acid Dissociation Constant (pKa)

11.66

Base Dissociation Constant (pKb)

3.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

Z218-0779 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Indole Derivatives (10091 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • Kinases
  • Kinases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with Z218-0779 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z218-0779?
Check Price and Availability of Z218-0779, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z218-0779 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z218-0779
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z218-0779
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z218-0779 available by request