Z218-2265 Screening compound: 3,4,5-triethoxy-N~1~-[3-(1-ethyl-3-methyl-1H-indol-2-yl)-1H-pyrazol-5-yl]benzamide

Z218-2265 Screening compound: 3,4,5-triethoxy-N~1~-[3-(1-ethyl-3-methyl-1H-indol-2-yl)-1H-pyrazol-5-yl]benzamide
Z218-2265 Screening compound: 3,4,5-triethoxy-N~1~-[3-(1-ethyl-3-methyl-1H-indol-2-yl)-1H-pyrazol-5-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z218-2265
3,4,5-triethoxy-N~1~-[3-(1-ethyl-3-methyl-1H-indol-2-yl)-1H-pyrazol-5-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z218-2265

Molecular Formula

C27H32N4O4 (C27 H32 N4 O4)

Compound Name

3,4,5-triethoxy-N~1~-[3-(1-ethyl-3-methyl-1H-indol-2-yl)-1H-pyrazol-5-yl]benzamide

IUPAC name

345-triethoxy-N-[3-(1-ethyl-3-methyl-1H-indol-2-yl)-1H-pyrazol-5-yl]benzamide

SMILES

CCn1c(-c2n[nH]c(NC(c(cc3OCC)cc(OCC)c3OCC)=O)c2)c(C)c2c1cccc2

InChI

InChI=1S/C27H32N4O4/c1-6-31-21-13-11-10-12-19(21)17(5)25(31)20-16-24(30-29-20)28-27(32)18-14-22(33-7-2)26(35-9-4)23(15-18)34-8-3/h10-16H,6-9H2,1-5H3,(H2,28,29,30,32)

InChI Key

QWYIXFYNULNCGH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27635258

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

476.58

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.136

Distribution Coefficient, logD

5.136

Water Solubility, LogSw

-5.23

Polar Surface Area

68.330

Acid Dissociation Constant (pKa)

11.25

Base Dissociation Constant (pKb)

-0.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.33

Z218-2265 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with Z218-2265 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z218-2265?
Check Price and Availability of Z218-2265, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z218-2265 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z218-2265
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z218-2265
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z218-2265 available by request