Z218-3061 Screening compound: N-[3-(1-ethyl-4-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]-2-(2-fluorophenyl)acetamide

Z218-3061 Screening compound: N-[3-(1-ethyl-4-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]-2-(2-fluorophenyl)acetamide
Z218-3061 Screening compound: N-[3-(1-ethyl-4-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]-2-(2-fluorophenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z218-3061
N-[3-(1-ethyl-4-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]-2-(2-fluorophenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z218-3061

Molecular Formula

C22H21FN4O2 (C22 H21 FN4 O2)

Compound Name

N-[3-(1-ethyl-4-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]-2-(2-fluorophenyl)acetamide

IUPAC name

N-[3-(1-ethyl-4-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]-2-(2-fluorophenyl)acetamide

SMILES

CCn(c(-c1n[nH]c(NC(Cc(cccc2)c2F)=O)c1)c1)c2c1c(OC)ccc2

InChI

InChI=1S/C22H21FN4O2/c1-3-27-18-9-6-10-20(29-2)15(18)12-19(27)17-13-21(26-25-17)24-22(28)11-14-7-4-5-8-16(14)23/h4-10,12-13H,3,11H2,1-2H3,(H2,24,25,26,28)

InChI Key

NDENUYSUJWWFET-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27635330

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.402

Distribution Coefficient, logD

4.402

Water Solubility, LogSw

-4.40

Polar Surface Area

54.254

Acid Dissociation Constant (pKa)

12.89

Base Dissociation Constant (pKb)

0.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

Z218-3061 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with Z218-3061 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z218-3061?
Check Price and Availability of Z218-3061, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z218-3061 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z218-3061
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z218-3061
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z218-3061 available by request