Z218-4400 Screening compound: 3-cyclopentyl-N-[3-(1-ethyl-6-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]propanamide

Z218-4400 Screening compound: 3-cyclopentyl-N-[3-(1-ethyl-6-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]propanamide
Z218-4400 Screening compound: 3-cyclopentyl-N-[3-(1-ethyl-6-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z218-4400
3-cyclopentyl-N-[3-(1-ethyl-6-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z218-4400

Molecular Formula

C22H28N4O2 (C22 H28 N4 O2)

Compound Name

3-cyclopentyl-N-[3-(1-ethyl-6-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]propanamide

IUPAC name

3-cyclopentyl-N-[3-(1-ethyl-6-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]propanamide

SMILES

CCn(c(-c1n[nH]c(NC(CCC2CCCC2)=O)c1)c1)c2c1ccc(OC)c2

InChI

InChI=1S/C22H28N4O2/c1-3-26-19-13-17(28-2)10-9-16(19)12-20(26)18-14-21(25-24-18)23-22(27)11-8-15-6-4-5-7-15/h9-10,12-15H,3-8,11H2,1-2H3,(H2,23,24,25,27)

InChI Key

UTBLKHQSHQJHSB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27635357

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.656

Distribution Coefficient, logD

4.656

Water Solubility, LogSw

-4.61

Polar Surface Area

54.725

Acid Dissociation Constant (pKa)

13.18

Base Dissociation Constant (pKb)

-0.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.50

Z218-4400 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Anti-Inflammatory Library (24602 compounds)

C-Met Library (15277 compounds)

Indole Derivatives (10091 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Cyclic compounds
Therapeutical areas:
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with Z218-4400 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z218-4400?
Check Price and Availability of Z218-4400, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z218-4400 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z218-4400
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z218-4400
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z218-4400 available by request