Z218-4418 Screening compound: N-[3-(1-ethyl-6-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]pyrazine-2-carboxamide
Chemical Structure Depiction of ChemDiv screening compound Z218-4418
N-[3-(1-ethyl-6-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]pyrazine-2-carboxamide
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
Z218-4418
Molecular Formula
C19H18N6O2 (C19 H18 N6 O2)
Compound Name
N-[3-(1-ethyl-6-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]pyrazine-2-carboxamide
IUPAC name
N-[3-(1-ethyl-6-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]pyrazine-2-carboxamide
SMILES
CCn(c(-c1n[nH]c(NC(c2nccnc2)=O)c1)c1)c2c1ccc(OC)c2
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
362.39
Hydrogen Bond Acceptors Count
6.00
Hydrogen Bond Donors Count
2.00
Rotatable Bond Count
6.00
Number of Nitrogen and Oxygen Atoms
8
Partition Coefficient, logP
2.494
Distribution Coefficient, logD
2.494
Water Solubility, LogSw
-2.71
Polar Surface Area
72.946
Acid Dissociation Constant (pKa)
11.52
Base Dissociation Constant (pKb)
-0.43
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
15.80
Z218-4418 in Drug Discovery
Included in Screening Libraries
Allosteric Kinases Inhibitors Library (23117 compounds)
Anti-Inflammatory Library (24602 compounds)
Anticancer Library (62698 compounds)
C-Met Library (15277 compounds)
Indole Derivatives (10091 compounds)
Anti-HIV1 Library (19540 compounds)
Included in 1.7M Stock Database
- Cancer
- Female
- Congenital
- Skin
- Immune system
- Cancer
- Cancer
- Digestive system
- Respiratory tract
- Otorhinolaryngologic
- Endocrine
- Antiviral
- Infections
- Immune system
- Kinases
- Kinases
- Receptor's ligands
- Cyclic compounds
References: we are preparing a list of scientific research reports with Z218-4418 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)