Z218-4531 Screening compound: N-[3-(1-ethyl-6-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]-3-fluoro-4-methylbenzamide

Z218-4531 Screening compound: N-[3-(1-ethyl-6-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]-3-fluoro-4-methylbenzamide
Z218-4531 Screening compound: N-[3-(1-ethyl-6-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]-3-fluoro-4-methylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z218-4531
N-[3-(1-ethyl-6-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]-3-fluoro-4-methylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z218-4531

Molecular Formula

C22H21FN4O2 (C22 H21 FN4 O2)

Compound Name

N-[3-(1-ethyl-6-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]-3-fluoro-4-methylbenzamide

IUPAC name

N-[3-(1-ethyl-6-methoxy-1H-indol-2-yl)-1H-pyrazol-5-yl]-3-fluoro-4-methylbenzamide

SMILES

CCn(c(-c1n[nH]c(NC(c2cc(F)c(C)cc2)=O)c1)c1)c2c1ccc(OC)c2

InChI

InChI=1S/C22H21FN4O2/c1-4-27-19-11-16(29-3)8-7-14(19)10-20(27)18-12-21(26-25-18)24-22(28)15-6-5-13(2)17(23)9-15/h5-12H,4H2,1-3H3,(H2,24,25,26,28)

InChI Key

NMRUNGFGJZMLPQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27635420

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.877

Distribution Coefficient, logD

4.877

Water Solubility, LogSw

-4.78

Polar Surface Area

54.381

Acid Dissociation Constant (pKa)

11.00

Base Dissociation Constant (pKb)

-0.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

Z218-4531 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

C-Met Library (15277 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with Z218-4531 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z218-4531?
Check Price and Availability of Z218-4531, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z218-4531 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z218-4531
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z218-4531
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z218-4531 available by request