Z219-0035 Screening compound: N-(4-cyanophenyl)-6-methyl-3-[3-(morpholin-4-yl)propyl]-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide

Z219-0035 Screening compound: N-(4-cyanophenyl)-6-methyl-3-[3-(morpholin-4-yl)propyl]-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide
Z219-0035 Screening compound: N-(4-cyanophenyl)-6-methyl-3-[3-(morpholin-4-yl)propyl]-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z219-0035
N-(4-cyanophenyl)-6-methyl-3-[3-(morpholin-4-yl)propyl]-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z219-0035

Molecular Formula

C22H23N5O4 (C22 H23 N5 O4)

Compound Name

N-(4-cyanophenyl)-6-methyl-3-[3-(morpholin-4-yl)propyl]-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-carboxamide

IUPAC name

N-(4-cyanophenyl)-6-methyl-3-[3-(morpholin-4-yl)propyl]-4-oxo-3H4H-furo[23-d]pyrimidine-5-carboxamide

SMILES

Cc1c(C(Nc(cc2)ccc2C#N)=O)c(C(N(CCCN2CCOCC2)C=N2)=O)c2o1

InChI

InChI=1S/C22H23N5O4/c1-15-18(20(28)25-17-5-3-16(13-23)4-6-17)19-21(31-15)24-14-27(22(19)29)8-2-7-26-9-11-30-12-10-26/h3-6,14H,2,7-12H2,1H3,(H,25,28)

InChI Key

MXZYNNHQCDNNGI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27635440

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

421.46

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.880

Distribution Coefficient, logD

0.699

Water Solubility, LogSw

-1.98

Polar Surface Area

85.738

Acid Dissociation Constant (pKa)

8.76

Base Dissociation Constant (pKb)

7.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

Z219-0035 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Lipid Metabolism Library (9174 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with Z219-0035 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z219-0035?
Check Price and Availability of Z219-0035, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z219-0035 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z219-0035
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z219-0035
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z219-0035 available by request