Z223-0479 Screening compound: 2-[4-(morpholin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-N-[3-(trifluoromethyl)phenyl]acetamide

Z223-0479 Screening compound: 2-[4-(morpholin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-N-[3-(trifluoromethyl)phenyl]acetamide
Z223-0479 Screening compound: 2-[4-(morpholin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-N-[3-(trifluoromethyl)phenyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z223-0479
2-[4-(morpholin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-N-[3-(trifluoromethyl)phenyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z223-0479

Molecular Formula

C18H17F3N6O2 (C18 H17 F3 N6 O2)

Compound Name

2-[4-(morpholin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-N-[3-(trifluoromethyl)phenyl]acetamide

IUPAC name

2-[4-(morpholin-4-yl)-1H-pyrazolo[34-d]pyrimidin-1-yl]-N-[3-(trifluoromethyl)phenyl]acetamide

SMILES

O=C(Cn1ncc2c(N3CCOCC3)ncnc12)Nc1cccc(C(F)(F)F)c1

InChI

InChI=1S/C18H17F3N6O2/c19-18(20,21)12-2-1-3-13(8-12)25-15(28)10-27-17-14(9-24-27)16(22-11-23-17)26-4-6-29-7-5-26/h1-3,8-9,11H,4-7,10H2,(H,25,28)

InChI Key

MEEQKVNCMLZEOG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27635578

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.37

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.911

Distribution Coefficient, logD

2.910

Water Solubility, LogSw

-3.08

Polar Surface Area

68.782

Acid Dissociation Constant (pKa)

10.17

Base Dissociation Constant (pKb)

4.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

Z223-0479 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with Z223-0479 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z223-0479?
Check Price and Availability of Z223-0479, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z223-0479 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z223-0479
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z223-0479
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z223-0479 available by request