Z223-0571 Screening compound: 1-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-2-(4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-ethanone

Z223-0571 Screening compound: 1-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-2-(4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-ethanone
Z223-0571 Screening compound: 1-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-2-(4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-ethanone alternative view

Chemical Structure Depiction of ChemDiv screening compound Z223-0571
1-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-2-(4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-ethanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z223-0571

Molecular Formula

C18H24N6O4 (C18 H24 N6 O4)

Compound Name

1-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-2-(4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-ethanone

IUPAC name

n/a

SMILES

O=C(Cn1ncc2c(N3CCOCC3)ncnc12)N(CC1)CCC11OCCO1

InChI

InChI=1S/C18H24N6O4/c25-15(22-3-1-18(2-4-22)27-9-10-28-18)12-24-17-14(11-21-24)16(19-13-20-17)23-5-7-26-8-6-23/h11,13H,1-10,12H2

InChI Key

GNQBDMWNMNNWMW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27635610

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.43

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

-0.120

Distribution Coefficient, logD

-0.129

Water Solubility, LogSw

-0.73

Polar Surface Area

76.462

Acid Dissociation Constant (pKa)

19.72

Base Dissociation Constant (pKb)

5.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

66.67

Z223-0571 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Others
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with Z223-0571 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z223-0571?
Check Price and Availability of Z223-0571, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z223-0571 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z223-0571
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z223-0571
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z223-0571 available by request