Z223-1644 Screening compound: 1-(4-phenylpiperazin-1-yl)-2-[4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethan-1-one

Z223-1644 Screening compound: 1-(4-phenylpiperazin-1-yl)-2-[4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethan-1-one
Z223-1644 Screening compound: 1-(4-phenylpiperazin-1-yl)-2-[4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound Z223-1644
1-(4-phenylpiperazin-1-yl)-2-[4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z223-1644

Molecular Formula

C27H30N8O (C27 H30 N8 O)

Compound Name

1-(4-phenylpiperazin-1-yl)-2-[4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethan-1-one

IUPAC name

1-(4-phenylpiperazin-1-yl)-2-[4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[34-d]pyrimidin-1-yl]ethan-1-one

SMILES

O=C(Cn1ncc2c(N(CC3)CCN3c3ccccc3)ncnc12)N(CC1)CCN1c1ccccc1

InChI

InChI=1S/C27H30N8O/c36-25(33-15-11-31(12-16-33)22-7-3-1-4-8-22)20-35-27-24(19-30-35)26(28-21-29-27)34-17-13-32(14-18-34)23-9-5-2-6-10-23/h1-10,19,21H,11-18,20H2

InChI Key

JHYJQGIVARHTAH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27635755

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.59

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.247

Distribution Coefficient, logD

3.238

Water Solubility, LogSw

-3.01

Polar Surface Area

60.638

Acid Dissociation Constant (pKa)

19.72

Base Dissociation Constant (pKb)

5.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

Z223-1644 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with Z223-1644 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z223-1644?
Check Price and Availability of Z223-1644, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z223-1644 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z223-1644
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z223-1644
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z223-1644 available by request