Z223-1654 Screening compound: 2-[4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-N-(propan-2-yl)acetamide

Z223-1654 Screening compound: 2-[4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-N-(propan-2-yl)acetamide
Z223-1654 Screening compound: 2-[4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-N-(propan-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z223-1654
2-[4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-N-(propan-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z223-1654

Molecular Formula

C20H25N7O (C20 H25 N7 O)

Compound Name

2-[4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-N-(propan-2-yl)acetamide

IUPAC name

2-[4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[34-d]pyrimidin-1-yl]-N-(propan-2-yl)acetamide

SMILES

CC(C)NC(Cn1ncc2c(N(CC3)CCN3c3ccccc3)ncnc12)=O

InChI

InChI=1S/C20H25N7O/c1-15(2)24-18(28)13-27-20-17(12-23-27)19(21-14-22-20)26-10-8-25(9-11-26)16-6-4-3-5-7-16/h3-7,12,14-15H,8-11,13H2,1-2H3,(H,24,28)

InChI Key

MLCXOSDXRFGYJE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27635761

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.325

Distribution Coefficient, logD

2.323

Water Solubility, LogSw

-2.55

Polar Surface Area

64.702

Acid Dissociation Constant (pKa)

15.40

Base Dissociation Constant (pKb)

4.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

Z223-1654 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

STING Agonist Library (5895 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Cancer
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with Z223-1654 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z223-1654?
Check Price and Availability of Z223-1654, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z223-1654 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z223-1654
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z223-1654
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z223-1654 available by request