Z223-1697 Screening compound: 1-(4-ethylpiperazino)-2-[4-(4-phenylpiperazino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-ethanone

Z223-1697 Screening compound: 1-(4-ethylpiperazino)-2-[4-(4-phenylpiperazino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-ethanone
Z223-1697 Screening compound: 1-(4-ethylpiperazino)-2-[4-(4-phenylpiperazino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-ethanone alternative view

Chemical Structure Depiction of ChemDiv screening compound Z223-1697
1-(4-ethylpiperazino)-2-[4-(4-phenylpiperazino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-ethanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z223-1697

Molecular Formula

C23H30N8O (C23 H30 N8 O)

Compound Name

1-(4-ethylpiperazino)-2-[4-(4-phenylpiperazino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-ethanone

IUPAC name

1-(4-ethylpiperazin-1-yl)-2-[4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[34-d]pyrimidin-1-yl]ethan-1-one

SMILES

CCN(CC1)CCN1C(Cn1ncc2c(N(CC3)CCN3c3ccccc3)ncnc12)=O

InChI

InChI=1S/C23H30N8O/c1-2-27-8-10-29(11-9-27)21(32)17-31-23-20(16-26-31)22(24-18-25-23)30-14-12-28(13-15-30)19-6-4-3-5-7-19/h3-7,16,18H,2,8-15,17H2,1H3

InChI Key

BNNJJLUNJTZKPV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27635781

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.774

Distribution Coefficient, logD

1.598

Water Solubility, LogSw

-2.02

Polar Surface Area

60.914

Acid Dissociation Constant (pKa)

19.72

Base Dissociation Constant (pKb)

7.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.83

Z223-1697 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with Z223-1697 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z223-1697?
Check Price and Availability of Z223-1697, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z223-1697 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z223-1697
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z223-1697
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z223-1697 available by request