Z223-1794 Screening compound: 2-[4-(4-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-N-[3-(trifluoromethyl)phenyl]acetamide

Z223-1794 Screening compound: 2-[4-(4-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-N-[3-(trifluoromethyl)phenyl]acetamide
Z223-1794 Screening compound: 2-[4-(4-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-N-[3-(trifluoromethyl)phenyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z223-1794
2-[4-(4-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-N-[3-(trifluoromethyl)phenyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z223-1794

Molecular Formula

C20H21F3N6O (C20 H21 F3 N6 O)

Compound Name

2-[4-(4-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-N-[3-(trifluoromethyl)phenyl]acetamide

IUPAC name

2-[4-(4-methylpiperidin-1-yl)-1H-pyrazolo[34-d]pyrimidin-1-yl]-N-[3-(trifluoromethyl)phenyl]acetamide

SMILES

CC(CC1)CCN1c1c(cnn2CC(Nc3cccc(C(F)(F)F)c3)=O)c2ncn1

InChI

InChI=1S/C20H21F3N6O/c1-13-5-7-28(8-6-13)18-16-10-26-29(19(16)25-12-24-18)11-17(30)27-15-4-2-3-14(9-15)20(21,22)23/h2-4,9-10,12-13H,5-8,11H2,1H3,(H,27,30)

InChI Key

DVWPEVTWIGZKNL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27635801

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.400

Distribution Coefficient, logD

4.399

Water Solubility, LogSw

-4.13

Polar Surface Area

60.874

Acid Dissociation Constant (pKa)

10.17

Base Dissociation Constant (pKb)

4.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

Z223-1794 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Phosphatases

References: we are preparing a list of scientific research reports with Z223-1794 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z223-1794?
Check Price and Availability of Z223-1794, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z223-1794 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z223-1794
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z223-1794
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z223-1794 available by request