Z236-1049 Screening compound: N~1~-[1,2,4]triazolo[4,3-a]pyridin-3-yl-2-(trifluoromethyl)benzamide

Z236-1049 Screening compound: N~1~-[1,2,4]triazolo[4,3-a]pyridin-3-yl-2-(trifluoromethyl)benzamide
Z236-1049 Screening compound: N~1~-[1,2,4]triazolo[4,3-a]pyridin-3-yl-2-(trifluoromethyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z236-1049
N~1~-[1,2,4]triazolo[4,3-a]pyridin-3-yl-2-(trifluoromethyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z236-1049

Molecular Formula

C14H9F3N4O (C14 H9 F3 N4 O)

Compound Name

N~1~-[1,2,4]triazolo[4,3-a]pyridin-3-yl-2-(trifluoromethyl)benzamide

IUPAC name

n/a

SMILES

O=C(c1c(C(F)(F)F)cccc1)Nc1nnc2n1cccc2

InChI

InChI=1S/C14H9F3N4O/c15-14(16,17)10-6-2-1-5-9(10)12(22)18-13-20-19-11-7-3-4-8-21(11)13/h1-8H,(H,18,20,22)

InChI Key

PTXHLAWMJHJRCV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27636188

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

306.25

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.811

Distribution Coefficient, logD

-0.223

Water Solubility, LogSw

-2.35

Polar Surface Area

46.847

Acid Dissociation Constant (pKa)

5.37

Base Dissociation Constant (pKb)

-11.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.10

Z236-1049 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with Z236-1049 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z236-1049?
Check Price and Availability of Z236-1049, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z236-1049 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z236-1049
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z236-1049
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z236-1049 available by request