Z236-1736 Screening compound: N-{5-ethoxy-[1,2,4]triazolo[4,3-a]pyridin-3-yl}-4-(trifluoromethoxy)benzamide

Z236-1736 Screening compound: N-{5-ethoxy-[1,2,4]triazolo[4,3-a]pyridin-3-yl}-4-(trifluoromethoxy)benzamide
Z236-1736 Screening compound: N-{5-ethoxy-[1,2,4]triazolo[4,3-a]pyridin-3-yl}-4-(trifluoromethoxy)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z236-1736
N-{5-ethoxy-[1,2,4]triazolo[4,3-a]pyridin-3-yl}-4-(trifluoromethoxy)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z236-1736

Molecular Formula

C16H13F3N4O3 (C16 H13 F3 N4 O3)

Compound Name

N-{5-ethoxy-[1,2,4]triazolo[4,3-a]pyridin-3-yl}-4-(trifluoromethoxy)benzamide

IUPAC name

N-{5-ethoxy-[124]triazolo[43-a]pyridin-3-yl}-4-(trifluoromethoxy)benzamide

SMILES

CCOc1cccc2nnc(NC(c(cc3)ccc3OC(F)(F)F)=O)n12

InChI

InChI=1S/C16H13F3N4O3/c1-2-25-13-5-3-4-12-21-22-15(23(12)13)20-14(24)10-6-8-11(9-7-10)26-16(17,18)19/h3-9H,2H2,1H3,(H,20,22,24)

InChI Key

DBCHSQKLTPQTJG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27636202

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

366.3

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.891

Distribution Coefficient, logD

3.645

Water Solubility, LogSw

-4.06

Polar Surface Area

58.981

Acid Dissociation Constant (pKa)

7.52

Base Dissociation Constant (pKb)

1.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.80

Z236-1736 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with Z236-1736 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z236-1736?
Check Price and Availability of Z236-1736, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z236-1736 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z236-1736
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z236-1736
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z236-1736 available by request