Z237-0522 Screening compound: N-[(2H-1,3-benzodioxol-5-yl)methyl]-3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-7-carboxamide

Z237-0522 Screening compound: N-[(2H-1,3-benzodioxol-5-yl)methyl]-3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-7-carboxamide
Z237-0522 Screening compound: N-[(2H-1,3-benzodioxol-5-yl)methyl]-3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z237-0522
N-[(2H-1,3-benzodioxol-5-yl)methyl]-3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z237-0522

Molecular Formula

C21H15FN4O3 (C21 H15 FN4 O3)

Compound Name

N-[(2H-1,3-benzodioxol-5-yl)methyl]-3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-7-carboxamide

IUPAC name

N-[(2H-13-benzodioxol-5-yl)methyl]-3-(4-fluorophenyl)-[124]triazolo[43-a]pyridine-7-carboxamide

SMILES

O=C(c1cc2nnc(-c(cc3)ccc3F)n2cc1)NCc(cc1)cc2c1OCO2

InChI

InChI=1S/C21H15FN4O3/c22-16-4-2-14(3-5-16)20-25-24-19-10-15(7-8-26(19)20)21(27)23-11-13-1-6-17-18(9-13)29-12-28-17/h1-10H,11-12H2,(H,23,27)

InChI Key

SBNSGCFQSIDFDD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27636303

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.37

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.036

Distribution Coefficient, logD

3.036

Water Solubility, LogSw

-3.27

Polar Surface Area

63.106

Acid Dissociation Constant (pKa)

13.04

Base Dissociation Constant (pKb)

-0.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

Z237-0522 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with Z237-0522 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z237-0522?
Check Price and Availability of Z237-0522, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z237-0522 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z237-0522
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z237-0522
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z237-0522 available by request