Z237-1039 Screening compound: N-(1-benzylpiperidin-4-yl)-3-(3,5-difluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-7-carboxamide

Z237-1039 Screening compound: N-(1-benzylpiperidin-4-yl)-3-(3,5-difluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-7-carboxamide
Z237-1039 Screening compound: N-(1-benzylpiperidin-4-yl)-3-(3,5-difluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z237-1039
N-(1-benzylpiperidin-4-yl)-3-(3,5-difluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z237-1039

Molecular Formula

C25H23F2N5O (C25 H23 F2 N5 O)

Compound Name

N-(1-benzylpiperidin-4-yl)-3-(3,5-difluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-7-carboxamide

IUPAC name

N-(1-benzylpiperidin-4-yl)-3-(35-difluorophenyl)-[124]triazolo[43-a]pyridine-7-carboxamide

SMILES

O=C(c1cc2nnc(-c3cc(F)cc(F)c3)n2cc1)NC1CCN(Cc2ccccc2)CC1

InChI

InChI=1S/C25H23F2N5O/c26-20-12-19(13-21(27)15-20)24-30-29-23-14-18(6-11-32(23)24)25(33)28-22-7-9-31(10-8-22)16-17-4-2-1-3-5-17/h1-6,11-15,22H,7-10,16H2,(H,28,33)

InChI Key

DHDVWBBRMSZXAW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27636414

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.568

Distribution Coefficient, logD

2.123

Water Solubility, LogSw

-3.68

Polar Surface Area

49.256

Acid Dissociation Constant (pKa)

14.67

Base Dissociation Constant (pKb)

8.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

Z237-1039 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with Z237-1039 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z237-1039?
Check Price and Availability of Z237-1039, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z237-1039 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z237-1039
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z237-1039
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z237-1039 available by request