Z237-1578 Screening compound: 3-(4-bromophenyl)-N-[(3,5-dimethoxyphenyl)methyl]-[1,2,4]triazolo[4,3-a]pyridine-7-carboxamide

Z237-1578 Screening compound: 3-(4-bromophenyl)-N-[(3,5-dimethoxyphenyl)methyl]-[1,2,4]triazolo[4,3-a]pyridine-7-carboxamide
Z237-1578 Screening compound: 3-(4-bromophenyl)-N-[(3,5-dimethoxyphenyl)methyl]-[1,2,4]triazolo[4,3-a]pyridine-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z237-1578
3-(4-bromophenyl)-N-[(3,5-dimethoxyphenyl)methyl]-[1,2,4]triazolo[4,3-a]pyridine-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z237-1578

Molecular Formula

C22H19BrN4O3 (C22 H19 BrN4 O3)

Compound Name

3-(4-bromophenyl)-N-[(3,5-dimethoxyphenyl)methyl]-[1,2,4]triazolo[4,3-a]pyridine-7-carboxamide

IUPAC name

3-(4-bromophenyl)-N-[(35-dimethoxyphenyl)methyl]-[124]triazolo[43-a]pyridine-7-carboxamide

SMILES

COc1cc(CNC(c2cc3nnc(-c(cc4)ccc4Br)n3cc2)=O)cc(OC)c1

InChI

InChI=1S/C22H19BrN4O3/c1-29-18-9-14(10-19(12-18)30-2)13-24-22(28)16-7-8-27-20(11-16)25-26-21(27)15-3-5-17(23)6-4-15/h3-12H,13H2,1-2H3,(H,24,28)

InChI Key

GFZQYYQFAWGMJJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27636495

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.32

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.178

Distribution Coefficient, logD

4.178

Water Solubility, LogSw

-4.30

Polar Surface Area

61.078

Acid Dissociation Constant (pKa)

12.54

Base Dissociation Constant (pKb)

-1.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

Z237-1578 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with Z237-1578 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z237-1578?
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What is the minimum amount of Z237-1578 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z237-1578
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z237-1578
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z237-1578 available by request