Z250-0045 Screening compound: ethyl 1-[7-(4-methylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]-3-piperidinecarboxylate

Z250-0045 Screening compound: ethyl 1-[7-(4-methylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]-3-piperidinecarboxylate
Z250-0045 Screening compound: ethyl 1-[7-(4-methylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]-3-piperidinecarboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound Z250-0045
ethyl 1-[7-(4-methylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]-3-piperidinecarboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z250-0045

Molecular Formula

C21H23N3O3S (C21 H23 N3 O3 S)

Compound Name

ethyl 1-[7-(4-methylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]-3-piperidinecarboxylate

IUPAC name

ethyl 1-[7-(4-methylphenyl)-4-oxo-3H4H-thieno[32-d]pyrimidin-2-yl]piperidine-3-carboxylate

SMILES

CCOC(C(CCC1)CN1C(NC1=O)=Nc2c1scc2-c1ccc(C)cc1)=O

InChI

InChI=1S/C21H23N3O3S/c1-3-27-20(26)15-5-4-10-24(11-15)21-22-17-16(12-28-18(17)19(25)23-21)14-8-6-13(2)7-9-14/h6-9,12,15H,3-5,10-11H2,1-2H3,(H,22,23,25)/t15-/m0/s1

InChI Key

DWEFNUQXNYNCRO-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD27636816

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.963

Distribution Coefficient, logD

3.963

Water Solubility, LogSw

-3.94

Polar Surface Area

57.139

Acid Dissociation Constant (pKa)

11.09

Base Dissociation Constant (pKb)

-2.31

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.10

Z250-0045 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with Z250-0045 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z250-0045?
Check Price and Availability of Z250-0045, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z250-0045 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z250-0045
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z250-0045
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z250-0045 available by request