Z250-1132 Screening compound: 1-[7-(2-fluorophenyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl]-N-[(pyridin-3-yl)methyl]piperidine-4-carboxamide

Chemical Structure Depiction of ChemDiv screening compound Z250-1132
1-[7-(2-fluorophenyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl]-N-[(pyridin-3-yl)methyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

Glass Vials (4ml Glass Vials VWR #97047-678)
96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Check Price and Availability

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z250-1132

Molecular Formula

C₂₄H₂₂FN₅O₂S (C24 H22 FN5 O2 S)

Compound Name

1-[7-(2-fluorophenyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl]-N-[(pyridin-3-yl)methyl]piperidine-4-carboxamide

IUPAC name

1-[7-(2-fluorophenyl)-4-oxo-3H4H-thieno[32-d]pyrimidin-2-yl]-N-[(pyridin-3-yl)methyl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1C(NC1=O)=Nc2c1scc2-c(cccc1)c1F)NCc1cnccc1

InChI

InChI=1S/C24H22FN5O2S/c25-19-6-2-1-5-17(19)18-14-33-21-20(18)28-24(29-23(21)32)30-10-7-16(8-11-30)22(31)27-13-15-4-3-9-26-12-15/h1-6,9,12,14,16H,7-8,10-11,13H2,(H,27,31)(H,28,29,32)

InChI Key

JODDLLKKTKCZQH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD22597263

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

Partition Coefficient, logP

2.242

Distribution Coefficient, logD

2.240

Water Solubility, LogSw

-2.67

Polar Surface Area

70.383

Acid Dissociation Constant (pK_a)

11.18

Base Dissociation Constant (pK_b)

5.15

Number of Chiral Centers

0.00

Percent sp³ carbon bonding

25.00

Z250-1132 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PLpro Library (6343 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:

Antiviral
Infections
Immune system
Musculoskeletal
Respiratory tract
Nervous system
Congenital
Skin
Metabolic
Endocrine
Hemic and lymphatic
Cardiovascular
Antiviral
Infections
Immune system
Infections
Cancer
Musculoskeletal
Digestive system
Respiratory tract
Male
Female
Cardiovascular
Skin
Metabolic
Immune system

Targets:

GPCR
Proteases

Mechanism of action:

Receptor's ligands
PPI modulators
PPI modulators
PPI modulators

Structure:

Mimetics
Mimetics

References: we are preparing a list of scientific research reports with Z250-1132 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z250-1132?
Check Price and Availability of Z250-1132, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.

What is the minimum amount of Z250-1132 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.

Delivery options for Z250-1132
ChemDiv sends parcels with Express services (UPS, WC).

1–2 days for small orders
2–4 weeks for large selections

Delivery formats for Z250-1132

0.5–50 mg of dry powder sample in single glass vials, custom vials
DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z250-1132 available by request