Z250-2676 Screening compound: 7-(3-METHYLPHENYL)-2-{4-[4-(PROPAN-2-YL)PIPERAZINE-1-CARBONYL]PIPERIDIN-1-YL}-3H,4H-THIENO[3,2-D]PYRIMIDIN-4-ONE

Z250-2676 Screening compound: 7-(3-METHYLPHENYL)-2-{4-[4-(PROPAN-2-YL)PIPERAZINE-1-CARBONYL]PIPERIDIN-1-YL}-3H,4H-THIENO[3,2-D]PYRIMIDIN-4-ONE
Z250-2676 Screening compound: 7-(3-METHYLPHENYL)-2-{4-[4-(PROPAN-2-YL)PIPERAZINE-1-CARBONYL]PIPERIDIN-1-YL}-3H,4H-THIENO[3,2-D]PYRIMIDIN-4-ONE alternative view

Chemical Structure Depiction of ChemDiv screening compound Z250-2676
7-(3-METHYLPHENYL)-2-{4-[4-(PROPAN-2-YL)PIPERAZINE-1-CARBONYL]PIPERIDIN-1-YL}-3H,4H-THIENO[3,2-D]PYRIMIDIN-4-ONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z250-2676

Molecular Formula

C26H33N5O2S (C26 H33 N5 O2 S)

Compound Name

7-(3-METHYLPHENYL)-2-{4-[4-(PROPAN-2-YL)PIPERAZINE-1-CARBONYL]PIPERIDIN-1-YL}-3H,4H-THIENO[3,2-D]PYRIMIDIN-4-ONE

IUPAC name

n/a

SMILES

CC(C)N(CC1)CCN1C(C(CC1)CCN1C(NC1=O)=Nc2c1scc2-c1cc(C)ccc1)=O

InChI

InChI=1S/C26H33N5O2S/c1-17(2)29-11-13-30(14-12-29)25(33)19-7-9-31(10-8-19)26-27-22-21(16-34-23(22)24(32)28-26)20-6-4-5-18(3)15-20/h4-6,15-17,19H,7-14H2,1-3H3,(H,27,28,32)

InChI Key

HLMNBDBRNPYNGH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27642549

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.65

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.568

Distribution Coefficient, logD

2.866

Water Solubility, LogSw

-3.75

Polar Surface Area

56.964

Acid Dissociation Constant (pKa)

11.18

Base Dissociation Constant (pKb)

8.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

Z250-2676 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with Z250-2676 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z250-2676?
Check Price and Availability of Z250-2676, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z250-2676 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z250-2676
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z250-2676
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z250-2676 available by request