Z253-0559 Screening compound: 7-[(4-benzylpiperidino)carbonyl]-3-cyclopropyl-6-methylthieno[3,2-d]pyrimidin-4(3H)-one

Z253-0559 Screening compound: 7-[(4-benzylpiperidino)carbonyl]-3-cyclopropyl-6-methylthieno[3,2-d]pyrimidin-4(3H)-one
Z253-0559 Screening compound: 7-[(4-benzylpiperidino)carbonyl]-3-cyclopropyl-6-methylthieno[3,2-d]pyrimidin-4(3H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound Z253-0559
7-[(4-benzylpiperidino)carbonyl]-3-cyclopropyl-6-methylthieno[3,2-d]pyrimidin-4(3H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z253-0559

Molecular Formula

C23H25N3O2S (C23 H25 N3 O2 S)

Compound Name

7-[(4-benzylpiperidino)carbonyl]-3-cyclopropyl-6-methylthieno[3,2-d]pyrimidin-4(3H)-one

IUPAC name

n/a

SMILES

Cc1c(C(N2CCC(Cc3ccccc3)CC2)=O)c(N=CN(C2CC2)C2=O)c2s1

InChI

InChI=1S/C23H25N3O2S/c1-15-19(20-21(29-15)23(28)26(14-24-20)18-7-8-18)22(27)25-11-9-17(10-12-25)13-16-5-3-2-4-6-16/h2-6,14,17-18H,7-13H2,1H3

InChI Key

ZXRBPWXGKXHFEM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27637020

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.091

Distribution Coefficient, logD

4.091

Water Solubility, LogSw

-4.37

Polar Surface Area

41.200

Acid Dissociation Constant (pKa)

25.45

Base Dissociation Constant (pKb)

-2.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

Z253-0559 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with Z253-0559 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z253-0559?
Check Price and Availability of Z253-0559, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z253-0559 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z253-0559
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z253-0559
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z253-0559 available by request