Z266-0004C Screening compound: N-methyl-4-(2-{[3-(trifluoromethyl)phenyl]amino}-1H-1,3-benzodiazole-5-carbonyl)pyridine-2-carboxamide

Z266-0004C Screening compound: N-methyl-4-(2-{[3-(trifluoromethyl)phenyl]amino}-1H-1,3-benzodiazole-5-carbonyl)pyridine-2-carboxamide
Z266-0004C Screening compound: N-methyl-4-(2-{[3-(trifluoromethyl)phenyl]amino}-1H-1,3-benzodiazole-5-carbonyl)pyridine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z266-0004C
N-methyl-4-(2-{[3-(trifluoromethyl)phenyl]amino}-1H-1,3-benzodiazole-5-carbonyl)pyridine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z266-0004C

Molecular Formula

C22H16F3N5O2 (C22 H16 F3 N5 O2)

Compound Name

N-methyl-4-(2-{[3-(trifluoromethyl)phenyl]amino}-1H-1,3-benzodiazole-5-carbonyl)pyridine-2-carboxamide

IUPAC name

N-methyl-4-(2-{[3-(trifluoromethyl)phenyl]amino}-1H-13-benzodiazole-5-carbonyl)pyridine-2-carboxamide

SMILES

CNC(c1nccc(C(c(cc2)cc3c2[nH]c(Nc2cccc(C(F)(F)F)c2)n3)=O)c1)=O

InChI

InChI=1S/C22H16F3N5O2/c1-26-20(32)18-10-13(7-8-27-18)19(31)12-5-6-16-17(9-12)30-21(29-16)28-15-4-2-3-14(11-15)22(23,24)25/h2-11H,1H3,(H,26,32)(H2,28,29,30)

InChI Key

DZMJDXYSAYRNBD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27637146

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

439.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.041

Distribution Coefficient, logD

4.004

Water Solubility, LogSw

-4.26

Polar Surface Area

76.926

Acid Dissociation Constant (pKa)

13.97

Base Dissociation Constant (pKb)

6.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

Z266-0004C in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with Z266-0004C chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z266-0004C?
Check Price and Availability of Z266-0004C, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z266-0004C you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z266-0004C
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z266-0004C
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z266-0004C available by request