Z266-0020C Screening compound: 4-[(2-{[4-chloro-3-(trifluoromethyl)phenyl]amino}-1H-1,3-benzodiazol-5-yl)amino]-N-methylpyridine-2-carboxamide

Z266-0020C Screening compound: 4-[(2-{[4-chloro-3-(trifluoromethyl)phenyl]amino}-1H-1,3-benzodiazol-5-yl)amino]-N-methylpyridine-2-carboxamide
Z266-0020C Screening compound: 4-[(2-{[4-chloro-3-(trifluoromethyl)phenyl]amino}-1H-1,3-benzodiazol-5-yl)amino]-N-methylpyridine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z266-0020C
4-[(2-{[4-chloro-3-(trifluoromethyl)phenyl]amino}-1H-1,3-benzodiazol-5-yl)amino]-N-methylpyridine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z266-0020C

Molecular Formula

C21H16ClF3N6O (C21 H16 ClF3 N6 O)

Compound Name

4-[(2-{[4-chloro-3-(trifluoromethyl)phenyl]amino}-1H-1,3-benzodiazol-5-yl)amino]-N-methylpyridine-2-carboxamide

IUPAC name

4-[(2-{[4-chloro-3-(trifluoromethyl)phenyl]amino}-1H-13-benzodiazol-5-yl)amino]-N-methylpyridine-2-carboxamide

SMILES

CNC(c1nccc(Nc(cc2)cc3c2[nH]c(Nc(cc2)cc(C(F)(F)F)c2Cl)n3)c1)=O

InChI

InChI=1S/C21H16ClF3N6O/c1-26-19(32)18-10-13(6-7-27-18)28-12-3-5-16-17(9-12)31-20(30-16)29-11-2-4-15(22)14(8-11)21(23,24)25/h2-10H,1H3,(H,26,32)(H,27,28)(H2,29,30,31)

InChI Key

HHMKGONIZGSDAI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27643737

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

460.85

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.884

Distribution Coefficient, logD

3.679

Water Solubility, LogSw

-4.96

Polar Surface Area

72.372

Acid Dissociation Constant (pKa)

15.92

Base Dissociation Constant (pKb)

8.58

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

Z266-0020C in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Angiogenesis library (14822 compounds)

Antifungal Library (16415 compounds)

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Proteases
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with Z266-0020C chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z266-0020C?
Check Price and Availability of Z266-0020C, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z266-0020C you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z266-0020C
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z266-0020C
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z266-0020C available by request