Z268-1157 Screening compound: 1-(4-bromo-2-fluorophenyl)-3-{5-chloro-[1,2,4]triazolo[4,3-a]pyridin-3-yl}urea

Z268-1157 Screening compound: 1-(4-bromo-2-fluorophenyl)-3-{5-chloro-[1,2,4]triazolo[4,3-a]pyridin-3-yl}urea
Z268-1157 Screening compound: 1-(4-bromo-2-fluorophenyl)-3-{5-chloro-[1,2,4]triazolo[4,3-a]pyridin-3-yl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound Z268-1157
1-(4-bromo-2-fluorophenyl)-3-{5-chloro-[1,2,4]triazolo[4,3-a]pyridin-3-yl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z268-1157

Molecular Formula

C13H8BrClFN5O (C13 H8 BrClFN5 O)

Compound Name

1-(4-bromo-2-fluorophenyl)-3-{5-chloro-[1,2,4]triazolo[4,3-a]pyridin-3-yl}urea

IUPAC name

1-(4-bromo-2-fluorophenyl)-3-{5-chloro-[124]triazolo[43-a]pyridin-3-yl}urea

SMILES

O=C(Nc1nnc2n1c(Cl)ccc2)Nc(ccc(Br)c1)c1F

InChI

InChI=1S/C13H8BrClFN5O/c14-7-4-5-9(8(16)6-7)17-13(22)18-12-20-19-11-3-1-2-10(15)21(11)12/h1-6H,(H2,17,18,20,22)

InChI Key

CTGMOFPVCWVBAE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27637248

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.59

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.602

Distribution Coefficient, logD

3.588

Water Solubility, LogSw

-3.92

Polar Surface Area

55.387

Acid Dissociation Constant (pKa)

8.89

Base Dissociation Constant (pKb)

-7.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

Z268-1157 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with Z268-1157 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z268-1157?
Check Price and Availability of Z268-1157, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z268-1157 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z268-1157
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z268-1157
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z268-1157 available by request