Z268-1199 Screening compound: 3-{5-ethoxy-[1,2,4]triazolo[4,3-a]pyridin-3-yl}-1-(3-fluorophenyl)urea

Z268-1199 Screening compound: 3-{5-ethoxy-[1,2,4]triazolo[4,3-a]pyridin-3-yl}-1-(3-fluorophenyl)urea
Z268-1199 Screening compound: 3-{5-ethoxy-[1,2,4]triazolo[4,3-a]pyridin-3-yl}-1-(3-fluorophenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound Z268-1199
3-{5-ethoxy-[1,2,4]triazolo[4,3-a]pyridin-3-yl}-1-(3-fluorophenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z268-1199

Molecular Formula

C15H14FN5O2 (C15 H14 FN5 O2)

Compound Name

3-{5-ethoxy-[1,2,4]triazolo[4,3-a]pyridin-3-yl}-1-(3-fluorophenyl)urea

IUPAC name

3-{5-ethoxy-[124]triazolo[43-a]pyridin-3-yl}-1-(3-fluorophenyl)urea

SMILES

CCOc1cccc2nnc(NC(Nc3cccc(F)c3)=O)n12

InChI

InChI=1S/C15H14FN5O2/c1-2-23-13-8-4-7-12-19-20-14(21(12)13)18-15(22)17-11-6-3-5-10(16)9-11/h3-9H,2H2,1H3,(H2,17,18,20,22)

InChI Key

CATARQPJCXDKMJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27643607

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

315.31

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.486

Distribution Coefficient, logD

3.465

Water Solubility, LogSw

-3.65

Polar Surface Area

62.256

Acid Dissociation Constant (pKa)

8.69

Base Dissociation Constant (pKb)

1.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.30

Z268-1199 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with Z268-1199 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z268-1199?
Check Price and Availability of Z268-1199, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z268-1199 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z268-1199
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z268-1199
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z268-1199 available by request