Z268-1285 Screening compound: 3-{5-ethoxy-[1,2,4]triazolo[4,3-a]pyridin-3-yl}-1-[(4-fluorophenyl)methyl]urea

Z268-1285 Screening compound: 3-{5-ethoxy-[1,2,4]triazolo[4,3-a]pyridin-3-yl}-1-[(4-fluorophenyl)methyl]urea
Z268-1285 Screening compound: 3-{5-ethoxy-[1,2,4]triazolo[4,3-a]pyridin-3-yl}-1-[(4-fluorophenyl)methyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound Z268-1285
3-{5-ethoxy-[1,2,4]triazolo[4,3-a]pyridin-3-yl}-1-[(4-fluorophenyl)methyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z268-1285

Molecular Formula

C16H16FN5O2 (C16 H16 FN5 O2)

Compound Name

3-{5-ethoxy-[1,2,4]triazolo[4,3-a]pyridin-3-yl}-1-[(4-fluorophenyl)methyl]urea

IUPAC name

3-{5-ethoxy-[124]triazolo[43-a]pyridin-3-yl}-1-[(4-fluorophenyl)methyl]urea

SMILES

CCOc1cccc2nnc(NC(NCc(cc3)ccc3F)=O)n12

InChI

InChI=1S/C16H16FN5O2/c1-2-24-14-5-3-4-13-20-21-15(22(13)14)19-16(23)18-10-11-6-8-12(17)9-7-11/h3-9H,2,10H2,1H3,(H2,18,19,21,23)

InChI Key

AUYLTYGKSVHFQT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27637299

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

329.33

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.578

Distribution Coefficient, logD

2.577

Water Solubility, LogSw

-2.86

Polar Surface Area

63.578

Acid Dissociation Constant (pKa)

10.06

Base Dissociation Constant (pKb)

-4.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.80

Z268-1285 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with Z268-1285 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z268-1285?
Check Price and Availability of Z268-1285, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z268-1285 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z268-1285
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z268-1285
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z268-1285 available by request