Z269-0296 Screening compound: 2-phenoxy-1-{4-[3-(piperidinocarbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidino}-1-ethanone

Z269-0296 Screening compound: 2-phenoxy-1-{4-[3-(piperidinocarbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidino}-1-ethanone
Z269-0296 Screening compound: 2-phenoxy-1-{4-[3-(piperidinocarbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidino}-1-ethanone alternative view

Chemical Structure Depiction of ChemDiv screening compound Z269-0296
2-phenoxy-1-{4-[3-(piperidinocarbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidino}-1-ethanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z269-0296

Molecular Formula

C26H30N4O3 (C26 H30 N4 O3)

Compound Name

2-phenoxy-1-{4-[3-(piperidinocarbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidino}-1-ethanone

IUPAC name

2-phenoxy-1-{4-[3-(piperidine-1-carbonyl)pyrazolo[15-a]pyridin-5-yl]piperidin-1-yl}ethan-1-one

SMILES

O=C(COc1ccccc1)N(CC1)CCC1c(ccn1nc2)cc1c2C(N1CCCCC1)=O

InChI

InChI=1S/C26H30N4O3/c31-25(19-33-22-7-3-1-4-8-22)28-14-9-20(10-15-28)21-11-16-30-24(17-21)23(18-27-30)26(32)29-12-5-2-6-13-29/h1,3-4,7-8,11,16-18,20H,2,5-6,9-10,12-15,19H2

InChI Key

IVHBRWHHGYTRLM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27637366

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.55

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.894

Distribution Coefficient, logD

2.894

Water Solubility, LogSw

-3.17

Polar Surface Area

51.333

Acid Dissociation Constant (pKa)

23.93

Base Dissociation Constant (pKb)

1.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.30

Z269-0296 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with Z269-0296 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z269-0296?
Check Price and Availability of Z269-0296, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z269-0296 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z269-0296
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z269-0296
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z269-0296 available by request