Z269-0302 Screening compound: {5-[1-(3-chloro-4-fluorobenzoyl)-4-piperidyl]pyrazolo[1,5-a]pyridin-3-yl}(piperidino)methanone

Z269-0302 Screening compound: {5-[1-(3-chloro-4-fluorobenzoyl)-4-piperidyl]pyrazolo[1,5-a]pyridin-3-yl}(piperidino)methanone
Z269-0302 Screening compound: {5-[1-(3-chloro-4-fluorobenzoyl)-4-piperidyl]pyrazolo[1,5-a]pyridin-3-yl}(piperidino)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound Z269-0302
{5-[1-(3-chloro-4-fluorobenzoyl)-4-piperidyl]pyrazolo[1,5-a]pyridin-3-yl}(piperidino)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z269-0302

Molecular Formula

C25H26ClFN4O2 (C25 H26 ClFN4 O2)

Compound Name

{5-[1-(3-chloro-4-fluorobenzoyl)-4-piperidyl]pyrazolo[1,5-a]pyridin-3-yl}(piperidino)methanone

IUPAC name

1-(3-chloro-4-fluorobenzoyl)-4-[3-(piperidine-1-carbonyl)pyrazolo[15-a]pyridin-5-yl]piperidine

SMILES

O=C(c1c(cc(C(CC2)CCN2C(c(cc2)cc(Cl)c2F)=O)cc2)n2nc1)N1CCCCC1

InChI

InChI=1S/C25H26ClFN4O2/c26-21-14-19(4-5-22(21)27)24(32)30-11-6-17(7-12-30)18-8-13-31-23(15-18)20(16-28-31)25(33)29-9-2-1-3-10-29/h4-5,8,13-17H,1-3,6-7,9-12H2

InChI Key

JRBBBGZJZXBQAM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27637370

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

468.96

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.597

Distribution Coefficient, logD

3.597

Water Solubility, LogSw

-4.10

Polar Surface Area

44.362

Acid Dissociation Constant (pKa)

23.93

Base Dissociation Constant (pKb)

1.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

Z269-0302 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with Z269-0302 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z269-0302?
Check Price and Availability of Z269-0302, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z269-0302 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z269-0302
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z269-0302
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z269-0302 available by request