Z271-0044 Screening compound: 1-(2,5-dimethylbenzenesulfonyl)-4-[3-(pyrrolidine-1-carbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidine

Z271-0044 Screening compound: 1-(2,5-dimethylbenzenesulfonyl)-4-[3-(pyrrolidine-1-carbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidine
Z271-0044 Screening compound: 1-(2,5-dimethylbenzenesulfonyl)-4-[3-(pyrrolidine-1-carbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound Z271-0044
1-(2,5-dimethylbenzenesulfonyl)-4-[3-(pyrrolidine-1-carbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z271-0044

Molecular Formula

C25H30N4O3S (C25 H30 N4 O3 S)

Compound Name

1-(2,5-dimethylbenzenesulfonyl)-4-[3-(pyrrolidine-1-carbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidine

IUPAC name

1-(25-dimethylbenzenesulfonyl)-4-[3-(pyrrolidine-1-carbonyl)pyrazolo[15-a]pyridin-5-yl]piperidine

SMILES

Cc1cc(S(N(CC2)CCC2c(ccn2nc3)cc2c3C(N2CCCC2)=O)(=O)=O)c(C)cc1

InChI

InChI=1S/C25H30N4O3S/c1-18-5-6-19(2)24(15-18)33(31,32)28-12-7-20(8-13-28)21-9-14-29-23(16-21)22(17-26-29)25(30)27-10-3-4-11-27/h5-6,9,14-17,20H,3-4,7-8,10-13H2,1-2H3

InChI Key

WPLQFWOERRFQOX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27637560

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

466.6

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.943

Distribution Coefficient, logD

3.943

Water Solubility, LogSw

-3.64

Polar Surface Area

59.790

Acid Dissociation Constant (pKa)

23.94

Base Dissociation Constant (pKb)

2.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

Z271-0044 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with Z271-0044 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z271-0044?
Check Price and Availability of Z271-0044, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z271-0044 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z271-0044
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z271-0044
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z271-0044 available by request