Z271-0061 Screening compound: 1-(2-chlorobenzenesulfonyl)-4-[3-(pyrrolidine-1-carbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidine

Z271-0061 Screening compound: 1-(2-chlorobenzenesulfonyl)-4-[3-(pyrrolidine-1-carbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidine
Z271-0061 Screening compound: 1-(2-chlorobenzenesulfonyl)-4-[3-(pyrrolidine-1-carbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound Z271-0061
1-(2-chlorobenzenesulfonyl)-4-[3-(pyrrolidine-1-carbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z271-0061

Molecular Formula

C23H25ClN4O3S (C23 H25 ClN4 O3 S)

Compound Name

1-(2-chlorobenzenesulfonyl)-4-[3-(pyrrolidine-1-carbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidine

IUPAC name

1-(2-chlorobenzenesulfonyl)-4-[3-(pyrrolidine-1-carbonyl)pyrazolo[15-a]pyridin-5-yl]piperidine

SMILES

O=C(c1c(cc(C(CC2)CCN2S(c(cccc2)c2Cl)(=O)=O)cc2)n2nc1)N1CCCC1

InChI

InChI=1S/C23H25ClN4O3S/c24-20-5-1-2-6-22(20)32(30,31)27-12-7-17(8-13-27)18-9-14-28-21(15-18)19(16-25-28)23(29)26-10-3-4-11-26/h1-2,5-6,9,14-17H,3-4,7-8,10-13H2

InChI Key

USIJHPRURQMWKJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27637575

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

473

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.341

Distribution Coefficient, logD

3.341

Water Solubility, LogSw

-3.65

Polar Surface Area

59.790

Acid Dissociation Constant (pKa)

23.94

Base Dissociation Constant (pKb)

2.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.13

Z271-0061 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with Z271-0061 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z271-0061?
Check Price and Availability of Z271-0061, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z271-0061 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z271-0061
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z271-0061
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z271-0061 available by request