Z271-0143 Screening compound: (5-{1-[(3-chlorophenyl)sulfonyl]-4-piperidyl}pyrazolo[1,5-a]pyridin-3-yl)(piperidino)methanone

Z271-0143 Screening compound: (5-{1-[(3-chlorophenyl)sulfonyl]-4-piperidyl}pyrazolo[1,5-a]pyridin-3-yl)(piperidino)methanone
Z271-0143 Screening compound: (5-{1-[(3-chlorophenyl)sulfonyl]-4-piperidyl}pyrazolo[1,5-a]pyridin-3-yl)(piperidino)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound Z271-0143
(5-{1-[(3-chlorophenyl)sulfonyl]-4-piperidyl}pyrazolo[1,5-a]pyridin-3-yl)(piperidino)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z271-0143

Molecular Formula

C24H27ClN4O3S (C24 H27 ClN4 O3 S)

Compound Name

(5-{1-[(3-chlorophenyl)sulfonyl]-4-piperidyl}pyrazolo[1,5-a]pyridin-3-yl)(piperidino)methanone

IUPAC name

1-(3-chlorobenzenesulfonyl)-4-[3-(piperidine-1-carbonyl)pyrazolo[15-a]pyridin-5-yl]piperidine

SMILES

O=C(c1c(cc(C(CC2)CCN2S(c2cccc(Cl)c2)(=O)=O)cc2)n2nc1)N1CCCCC1

InChI

InChI=1S/C24H27ClN4O3S/c25-20-5-4-6-21(16-20)33(31,32)28-12-7-18(8-13-28)19-9-14-29-23(15-19)22(17-26-29)24(30)27-10-2-1-3-11-27/h4-6,9,14-18H,1-3,7-8,10-13H2

InChI Key

VHJYYDVGGKJIGE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27637606

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

487.02

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.065

Distribution Coefficient, logD

4.065

Water Solubility, LogSw

-4.33

Polar Surface Area

59.424

Acid Dissociation Constant (pKa)

23.94

Base Dissociation Constant (pKb)

1.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.67

Z271-0143 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with Z271-0143 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z271-0143?
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What is the minimum amount of Z271-0143 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z271-0143
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z271-0143
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z271-0143 available by request