Z271-0145 Screening compound: 1-(2-chlorobenzenesulfonyl)-4-[3-(piperidine-1-carbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidine

Z271-0145 Screening compound: 1-(2-chlorobenzenesulfonyl)-4-[3-(piperidine-1-carbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidine
Z271-0145 Screening compound: 1-(2-chlorobenzenesulfonyl)-4-[3-(piperidine-1-carbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound Z271-0145
1-(2-chlorobenzenesulfonyl)-4-[3-(piperidine-1-carbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z271-0145

Molecular Formula

C24H27ClN4O3S (C24 H27 ClN4 O3 S)

Compound Name

1-(2-chlorobenzenesulfonyl)-4-[3-(piperidine-1-carbonyl)pyrazolo[1,5-a]pyridin-5-yl]piperidine

IUPAC name

1-(2-chlorobenzenesulfonyl)-4-[3-(piperidine-1-carbonyl)pyrazolo[15-a]pyridin-5-yl]piperidine

SMILES

O=C(c1c(cc(C(CC2)CCN2S(c(cccc2)c2Cl)(=O)=O)cc2)n2nc1)N1CCCCC1

InChI

InChI=1S/C24H27ClN4O3S/c25-21-6-2-3-7-23(21)33(31,32)28-13-8-18(9-14-28)19-10-15-29-22(16-19)20(17-26-29)24(30)27-11-4-1-5-12-27/h2-3,6-7,10,15-18H,1,4-5,8-9,11-14H2

InChI Key

YCLDWFPPZMIERG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27637607

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

487.02

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.629

Distribution Coefficient, logD

3.629

Water Solubility, LogSw

-4.00

Polar Surface Area

59.424

Acid Dissociation Constant (pKa)

23.94

Base Dissociation Constant (pKb)

2.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

Z271-0145 in Drug Discovery

Included in Screening Libraries

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with Z271-0145 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z271-0145?
Check Price and Availability of Z271-0145, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z271-0145 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z271-0145
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z271-0145
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z271-0145 available by request