Z274-0130 Screening compound: 2-[9-benzyl-4-(4-chlorophenyl)-1,5,9-triazaspiro[5.5]undec-4-en-2-yl]-4-chlorophenol

Z274-0130 Screening compound: 2-[9-benzyl-4-(4-chlorophenyl)-1,5,9-triazaspiro[5.5]undec-4-en-2-yl]-4-chlorophenol
Z274-0130 Screening compound: 2-[9-benzyl-4-(4-chlorophenyl)-1,5,9-triazaspiro[5.5]undec-4-en-2-yl]-4-chlorophenol alternative view

Chemical Structure Depiction of ChemDiv screening compound Z274-0130
2-[9-benzyl-4-(4-chlorophenyl)-1,5,9-triazaspiro[5.5]undec-4-en-2-yl]-4-chlorophenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z274-0130

Molecular Formula

C27H27Cl2N3O (C27 H27 Cl2 N3 O)

Compound Name

2-[9-benzyl-4-(4-chlorophenyl)-1,5,9-triazaspiro[5.5]undec-4-en-2-yl]-4-chlorophenol

IUPAC name

2-[9-benzyl-4-(4-chlorophenyl)-159-triazaspiro[5.5]undec-4-en-2-yl]-4-chlorophenol

SMILES

Oc(cc1)c(C(C2)NC3(CCN(Cc4ccccc4)CC3)N=C2c(cc2)ccc2Cl)cc1Cl

InChI

InChI=1S/C27H27Cl2N3O/c28-21-8-6-20(7-9-21)24-17-25(23-16-22(29)10-11-26(23)33)31-27(30-24)12-14-32(15-13-27)18-19-4-2-1-3-5-19/h1-11,16,25,31,33H,12-15,17-18H2/t25-/m0/s1

InChI Key

LITHVWGOKQDLLS-VWLOTQADSA-N

MDL Number (MFCD)

MFCD22390604

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.056

Distribution Coefficient, logD

4.811

Water Solubility, LogSw

-6.11

Polar Surface Area

41.068

Acid Dissociation Constant (pKa)

10.24

Base Dissociation Constant (pKb)

8.62

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

29.60

Z274-0130 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Eccentric PPI Library (11937 compounds)

Hsp90-Targeted Library (11355 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds
  • Cyclic compounds
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with Z274-0130 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z274-0130?
Check Price and Availability of Z274-0130, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z274-0130 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z274-0130
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z274-0130
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z274-0130 available by request