Z274-0412 Screening compound: 1-[2-(3,4-dimethylphenyl)-4-(2-hydroxy-3-methoxyphenyl)-1,5,9-triazaspiro[5.5]undec-1-en-9-yl]ethan-1-one

Z274-0412 Screening compound: 1-[2-(3,4-dimethylphenyl)-4-(2-hydroxy-3-methoxyphenyl)-1,5,9-triazaspiro[5.5]undec-1-en-9-yl]ethan-1-one
Z274-0412 Screening compound: 1-[2-(3,4-dimethylphenyl)-4-(2-hydroxy-3-methoxyphenyl)-1,5,9-triazaspiro[5.5]undec-1-en-9-yl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound Z274-0412
1-[2-(3,4-dimethylphenyl)-4-(2-hydroxy-3-methoxyphenyl)-1,5,9-triazaspiro[5.5]undec-1-en-9-yl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z274-0412

Molecular Formula

C25H31N3O3 (C25 H31 N3 O3)

Compound Name

1-[2-(3,4-dimethylphenyl)-4-(2-hydroxy-3-methoxyphenyl)-1,5,9-triazaspiro[5.5]undec-1-en-9-yl]ethan-1-one

IUPAC name

1-[2-(34-dimethylphenyl)-4-(2-hydroxy-3-methoxyphenyl)-159-triazaspiro[5.5]undec-1-en-9-yl]ethan-1-one

SMILES

CC(N(CC1)CCC1(NC(C1)c(cccc2OC)c2O)N=C1c1cc(C)c(C)cc1)=O

InChI

InChI=1S/C25H31N3O3/c1-16-8-9-19(14-17(16)2)21-15-22(20-6-5-7-23(31-4)24(20)30)27-25(26-21)10-12-28(13-11-25)18(3)29/h5-9,14,22,27,30H,10-13,15H2,1-4H3/t22-/m1/s1

InChI Key

XGFHQYVSMUMPRR-JOCHJYFZSA-N

MDL Number (MFCD)

MFCD22390950

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.816

Distribution Coefficient, logD

3.072

Water Solubility, LogSw

-3.85

Polar Surface Area

61.284

Acid Dissociation Constant (pKa)

10.27

Base Dissociation Constant (pKb)

8.06

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.00

Z274-0412 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with Z274-0412 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z274-0412?
Check Price and Availability of Z274-0412, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z274-0412 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z274-0412
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z274-0412
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z274-0412 available by request