Z274-0464 Screening compound: ethyl 4-(3-ethoxy-2-hydroxyphenyl)-2-(4-ethoxyphenyl)-1,5,9-triazaspiro[5.5]undec-1-ene-9-carboxylate

Z274-0464 Screening compound: ethyl 4-(3-ethoxy-2-hydroxyphenyl)-2-(4-ethoxyphenyl)-1,5,9-triazaspiro[5.5]undec-1-ene-9-carboxylate
Z274-0464 Screening compound: ethyl 4-(3-ethoxy-2-hydroxyphenyl)-2-(4-ethoxyphenyl)-1,5,9-triazaspiro[5.5]undec-1-ene-9-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound Z274-0464
ethyl 4-(3-ethoxy-2-hydroxyphenyl)-2-(4-ethoxyphenyl)-1,5,9-triazaspiro[5.5]undec-1-ene-9-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z274-0464

Molecular Formula

C27H35N3O5 (C27 H35 N3 O5)

Compound Name

ethyl 4-(3-ethoxy-2-hydroxyphenyl)-2-(4-ethoxyphenyl)-1,5,9-triazaspiro[5.5]undec-1-ene-9-carboxylate

IUPAC name

ethyl 4-(3-ethoxy-2-hydroxyphenyl)-2-(4-ethoxyphenyl)-159-triazaspiro[5.5]undec-1-ene-9-carboxylate

SMILES

CCOC(N(CC1)CCC1(NC(C1)c(cccc2OCC)c2O)N=C1c(cc1)ccc1OCC)=O

InChI

InChI=1S/C27H35N3O5/c1-4-33-20-12-10-19(11-13-20)22-18-23(21-8-7-9-24(25(21)31)34-5-2)29-27(28-22)14-16-30(17-15-27)26(32)35-6-3/h7-13,23,29,31H,4-6,14-18H2,1-3H3/t23-/m1/s1

InChI Key

ZTCRDAIDCZBYRR-HSZRJFAPSA-N

MDL Number (MFCD)

MFCD27637808

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.59

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.553

Distribution Coefficient, logD

3.888

Water Solubility, LogSw

-4.16

Polar Surface Area

73.572

Acid Dissociation Constant (pKa)

10.55

Base Dissociation Constant (pKb)

7.96

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

48.10

Z274-0464 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Eccentric PPI Library (11937 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with Z274-0464 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z274-0464?
Check Price and Availability of Z274-0464, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z274-0464 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z274-0464
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z274-0464
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z274-0464 available by request