Z298-0177 Screening compound: N-{1-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]piperidin-4-yl}cyclopentanecarboxamide

Z298-0177 Screening compound: N-{1-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]piperidin-4-yl}cyclopentanecarboxamide
Z298-0177 Screening compound: N-{1-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]piperidin-4-yl}cyclopentanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z298-0177
N-{1-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]piperidin-4-yl}cyclopentanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z298-0177

Molecular Formula

C22H26FN5OS (C22 H26 FN5 OS)

Compound Name

N-{1-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]piperidin-4-yl}cyclopentanecarboxamide

IUPAC name

N-{1-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[34-d][13]thiazol-5-yl]piperidin-4-yl}cyclopentanecarboxamide

SMILES

Cc(c1c2nc(N(CC3)CCC3NC(C3CCCC3)=O)s1)nn2-c(cc1)ccc1F

InChI

InChI=1S/C22H26FN5OS/c1-14-19-20(28(26-14)18-8-6-16(23)7-9-18)25-22(30-19)27-12-10-17(11-13-27)24-21(29)15-4-2-3-5-15/h6-9,15,17H,2-5,10-13H2,1H3,(H,24,29)

InChI Key

HZJVWUQMGUYJAB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27642328

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.55

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.265

Distribution Coefficient, logD

4.265

Water Solubility, LogSw

-4.09

Polar Surface Area

52.796

Acid Dissociation Constant (pKa)

15.70

Base Dissociation Constant (pKb)

4.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

Z298-0177 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with Z298-0177 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z298-0177?
Check Price and Availability of Z298-0177, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z298-0177 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z298-0177
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z298-0177
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z298-0177 available by request