Z298-0230 Screening compound: 1-ethyl-N-{1-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]piperidin-4-yl}-1H-pyrazole-5-carboxamide

Z298-0230 Screening compound: 1-ethyl-N-{1-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]piperidin-4-yl}-1H-pyrazole-5-carboxamide
Z298-0230 Screening compound: 1-ethyl-N-{1-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]piperidin-4-yl}-1H-pyrazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z298-0230
1-ethyl-N-{1-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]piperidin-4-yl}-1H-pyrazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z298-0230

Molecular Formula

C22H24FN7OS (C22 H24 FN7 OS)

Compound Name

1-ethyl-N-{1-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]piperidin-4-yl}-1H-pyrazole-5-carboxamide

IUPAC name

1-ethyl-N-{1-[1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[34-d][13]thiazol-5-yl]piperidin-4-yl}-1H-pyrazole-5-carboxamide

SMILES

CCn1nccc1C(NC(CC1)CCN1c1nc(n(-c(cc2)ccc2F)nc2C)c2s1)=O

InChI

InChI=1S/C22H24FN7OS/c1-3-29-18(8-11-24-29)21(31)25-16-9-12-28(13-10-16)22-26-20-19(32-22)14(2)27-30(20)17-6-4-15(23)5-7-17/h4-8,11,16H,3,9-10,12-13H2,1-2H3,(H,25,31)

InChI Key

XCKGRMPFYCOLEW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27638102

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.148

Distribution Coefficient, logD

3.148

Water Solubility, LogSw

-3.30

Polar Surface Area

65.327

Acid Dissociation Constant (pKa)

14.78

Base Dissociation Constant (pKb)

0.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

Z298-0230 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with Z298-0230 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z298-0230?
Check Price and Availability of Z298-0230, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z298-0230 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z298-0230
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z298-0230
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z298-0230 available by request