Z301-0378 Screening compound: 2-(3-methoxyphenoxy)-1-{4-[3-methyl-1-(4-methylphenyl)-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]-1,4-diazepan-1-yl}ethan-1-one

Z301-0378 Screening compound: 2-(3-methoxyphenoxy)-1-{4-[3-methyl-1-(4-methylphenyl)-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]-1,4-diazepan-1-yl}ethan-1-one
Z301-0378 Screening compound: 2-(3-methoxyphenoxy)-1-{4-[3-methyl-1-(4-methylphenyl)-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]-1,4-diazepan-1-yl}ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound Z301-0378
2-(3-methoxyphenoxy)-1-{4-[3-methyl-1-(4-methylphenyl)-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]-1,4-diazepan-1-yl}ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z301-0378

Molecular Formula

C26H29N5O3S (C26 H29 N5 O3 S)

Compound Name

2-(3-methoxyphenoxy)-1-{4-[3-methyl-1-(4-methylphenyl)-1H-pyrazolo[3,4-d][1,3]thiazol-5-yl]-1,4-diazepan-1-yl}ethan-1-one

IUPAC name

2-(3-methoxyphenoxy)-1-{4-[3-methyl-1-(4-methylphenyl)-1H-pyrazolo[34-d][13]thiazol-5-yl]-14-diazepan-1-yl}ethan-1-one

SMILES

Cc(c1c2nc(N(CCC3)CCN3C(COc3cc(OC)ccc3)=O)s1)nn2-c1ccc(C)cc1

InChI

InChI=1S/C26H29N5O3S/c1-18-8-10-20(11-9-18)31-25-24(19(2)28-31)35-26(27-25)30-13-5-12-29(14-15-30)23(32)17-34-22-7-4-6-21(16-22)33-3/h4,6-11,16H,5,12-15,17H2,1-3H3

InChI Key

QJRQJKMBUJWWEC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27638339

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

491.61

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.413

Distribution Coefficient, logD

4.413

Water Solubility, LogSw

-4.35

Polar Surface Area

59.594

Acid Dissociation Constant (pKa)

23.34

Base Dissociation Constant (pKb)

1.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

Z301-0378 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with Z301-0378 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z301-0378?
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What is the minimum amount of Z301-0378 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z301-0378
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z301-0378
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z301-0378 available by request