Z318-0356 Screening compound: N-[4-(3,4-dimethoxyphenyl)-3-methyl-1H-pyrazol-5-yl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide

Z318-0356 Screening compound: N-[4-(3,4-dimethoxyphenyl)-3-methyl-1H-pyrazol-5-yl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide
Z318-0356 Screening compound: N-[4-(3,4-dimethoxyphenyl)-3-methyl-1H-pyrazol-5-yl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z318-0356
N-[4-(3,4-dimethoxyphenyl)-3-methyl-1H-pyrazol-5-yl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z318-0356

Molecular Formula

C21H21N3O5 (C21 H21 N3 O5)

Compound Name

N-[4-(3,4-dimethoxyphenyl)-3-methyl-1H-pyrazol-5-yl]-2,3-dihydro-1,4-benzodioxine-2-carboxamide

IUPAC name

N-[4-(34-dimethoxyphenyl)-3-methyl-1H-pyrazol-5-yl]-23-dihydro-14-benzodioxine-2-carboxamide

SMILES

Cc1n[nH]c(NC(C2Oc(cccc3)c3OC2)=O)c1-c(cc1)cc(OC)c1OC

InChI

InChI=1S/C21H21N3O5/c1-12-19(13-8-9-14(26-2)17(10-13)27-3)20(24-23-12)22-21(25)18-11-28-15-6-4-5-7-16(15)29-18/h4-10,18H,11H2,1-3H3,(H2,22,23,24,25)/t18-/m0/s1

InChI Key

ZHEGEYAOVPAYDW-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27638442

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

395.41

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.557

Distribution Coefficient, logD

2.557

Water Solubility, LogSw

-3.03

Polar Surface Area

77.734

Acid Dissociation Constant (pKa)

10.38

Base Dissociation Constant (pKb)

0.15

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.80

Z318-0356 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with Z318-0356 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z318-0356?
Check Price and Availability of Z318-0356, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z318-0356 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z318-0356
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z318-0356
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z318-0356 available by request