Z341-0019 Screening compound: N~4~-(2-bromophenyl)-1-[3-methyl-5-(1-pyrrolidinylcarbonyl)isothiazolo[5,4-b]pyridin-4-yl]-4-piperidinecarboxamide

Z341-0019 Screening compound: N~4~-(2-bromophenyl)-1-[3-methyl-5-(1-pyrrolidinylcarbonyl)isothiazolo[5,4-b]pyridin-4-yl]-4-piperidinecarboxamide
Z341-0019 Screening compound: N~4~-(2-bromophenyl)-1-[3-methyl-5-(1-pyrrolidinylcarbonyl)isothiazolo[5,4-b]pyridin-4-yl]-4-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z341-0019
N~4~-(2-bromophenyl)-1-[3-methyl-5-(1-pyrrolidinylcarbonyl)isothiazolo[5,4-b]pyridin-4-yl]-4-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z341-0019

Molecular Formula

C24H26BrN5O2S (C24 H26 BrN5 O2 S)

Compound Name

N~4~-(2-bromophenyl)-1-[3-methyl-5-(1-pyrrolidinylcarbonyl)isothiazolo[5,4-b]pyridin-4-yl]-4-piperidinecarboxamide

IUPAC name

N-(2-bromophenyl)-1-[3-methyl-5-(pyrrolidine-1-carbonyl)-[12]thiazolo[54-b]pyridin-4-yl]piperidine-4-carboxamide

SMILES

Cc1nsc(nc2)c1c(N(CC1)CCC1C(Nc(cccc1)c1Br)=O)c2C(N1CCCC1)=O

InChI

InChI=1S/C24H26BrN5O2S/c1-15-20-21(17(14-26-23(20)33-28-15)24(32)30-10-4-5-11-30)29-12-8-16(9-13-29)22(31)27-19-7-3-2-6-18(19)25/h2-3,6-7,14,16H,4-5,8-13H2,1H3,(H,27,31)

InChI Key

BYEBOHUGHWZJDW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27638520

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

528.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.600

Distribution Coefficient, logD

3.599

Water Solubility, LogSw

-3.85

Polar Surface Area

62.789

Acid Dissociation Constant (pKa)

11.10

Base Dissociation Constant (pKb)

4.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.67

Z341-0019 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with Z341-0019 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z341-0019?
Check Price and Availability of Z341-0019, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z341-0019 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z341-0019
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z341-0019
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z341-0019 available by request