Z341-0655 Screening compound: N-(2-chloro-4-fluorophenyl)-1-[3-methyl-5-(morpholine-4-carbonyl)-[1,2]thiazolo[5,4-b]pyridin-4-yl]piperidine-4-carboxamide

Z341-0655 Screening compound: N-(2-chloro-4-fluorophenyl)-1-[3-methyl-5-(morpholine-4-carbonyl)-[1,2]thiazolo[5,4-b]pyridin-4-yl]piperidine-4-carboxamide
Z341-0655 Screening compound: N-(2-chloro-4-fluorophenyl)-1-[3-methyl-5-(morpholine-4-carbonyl)-[1,2]thiazolo[5,4-b]pyridin-4-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z341-0655
N-(2-chloro-4-fluorophenyl)-1-[3-methyl-5-(morpholine-4-carbonyl)-[1,2]thiazolo[5,4-b]pyridin-4-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z341-0655

Molecular Formula

C24H25ClFN5O3S (C24 H25 ClFN5 O3 S)

Compound Name

N-(2-chloro-4-fluorophenyl)-1-[3-methyl-5-(morpholine-4-carbonyl)-[1,2]thiazolo[5,4-b]pyridin-4-yl]piperidine-4-carboxamide

IUPAC name

N-(2-chloro-4-fluorophenyl)-1-[3-methyl-5-(morpholine-4-carbonyl)-[12]thiazolo[54-b]pyridin-4-yl]piperidine-4-carboxamide

SMILES

Cc1nsc(nc2)c1c(N(CC1)CCC1C(Nc(ccc(F)c1)c1Cl)=O)c2C(N1CCOCC1)=O

InChI

InChI=1S/C24H25ClFN5O3S/c1-14-20-21(17(13-27-23(20)35-29-14)24(33)31-8-10-34-11-9-31)30-6-4-15(5-7-30)22(32)28-19-3-2-16(26)12-18(19)25/h2-3,12-13,15H,4-11H2,1H3,(H,28,32)

InChI Key

QVPSCGNLHRQXFN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27638656

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

518.01

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.899

Distribution Coefficient, logD

2.856

Water Solubility, LogSw

-3.48

Polar Surface Area

70.331

Acid Dissociation Constant (pKa)

8.39

Base Dissociation Constant (pKb)

4.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

Z341-0655 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with Z341-0655 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z341-0655?
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What is the minimum amount of Z341-0655 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z341-0655
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z341-0655
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z341-0655 available by request