Z341-0851 Screening compound: N-(2,5-diethoxyphenyl)-1-[5-(diethylcarbamoyl)-3-methyl-[1,2]thiazolo[5,4-b]pyridin-4-yl]piperidine-4-carboxamide

Z341-0851 Screening compound: N-(2,5-diethoxyphenyl)-1-[5-(diethylcarbamoyl)-3-methyl-[1,2]thiazolo[5,4-b]pyridin-4-yl]piperidine-4-carboxamide
Z341-0851 Screening compound: N-(2,5-diethoxyphenyl)-1-[5-(diethylcarbamoyl)-3-methyl-[1,2]thiazolo[5,4-b]pyridin-4-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z341-0851
N-(2,5-diethoxyphenyl)-1-[5-(diethylcarbamoyl)-3-methyl-[1,2]thiazolo[5,4-b]pyridin-4-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z341-0851

Molecular Formula

C28H37N5O4S (C28 H37 N5 O4 S)

Compound Name

N-(2,5-diethoxyphenyl)-1-[5-(diethylcarbamoyl)-3-methyl-[1,2]thiazolo[5,4-b]pyridin-4-yl]piperidine-4-carboxamide

IUPAC name

N-(25-diethoxyphenyl)-1-[5-(diethylcarbamoyl)-3-methyl-[12]thiazolo[54-b]pyridin-4-yl]piperidine-4-carboxamide

SMILES

CCN(CC)C(c1cnc2snc(C)c2c1N(CC1)CCC1C(Nc(cc(cc1)OCC)c1OCC)=O)=O

InChI

InChI=1S/C28H37N5O4S/c1-6-32(7-2)28(35)21-17-29-27-24(18(5)31-38-27)25(21)33-14-12-19(13-15-33)26(34)30-22-16-20(36-8-3)10-11-23(22)37-9-4/h10-11,16-17,19H,6-9,12-15H2,1-5H3,(H,30,34)

InChI Key

QPFUKPXKWMZRFZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27638701

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

539.7

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.767

Distribution Coefficient, logD

3.764

Water Solubility, LogSw

-3.96

Polar Surface Area

76.040

Acid Dissociation Constant (pKa)

9.67

Base Dissociation Constant (pKb)

4.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

Z341-0851 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular

References: we are preparing a list of scientific research reports with Z341-0851 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z341-0851?
Check Price and Availability of Z341-0851, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z341-0851 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z341-0851
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z341-0851
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z341-0851 available by request