Z354-0054 Screening compound: 1-{2-ethyl-5-methylthieno[3,4-d]pyrimidin-4-yl}-N-[(4-methylphenyl)methyl]piperidine-4-carboxamide

Z354-0054 Screening compound: 1-{2-ethyl-5-methylthieno[3,4-d]pyrimidin-4-yl}-N-[(4-methylphenyl)methyl]piperidine-4-carboxamide
Z354-0054 Screening compound: 1-{2-ethyl-5-methylthieno[3,4-d]pyrimidin-4-yl}-N-[(4-methylphenyl)methyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z354-0054
1-{2-ethyl-5-methylthieno[3,4-d]pyrimidin-4-yl}-N-[(4-methylphenyl)methyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z354-0054

Molecular Formula

C23H28N4OS (C23 H28 N4 OS)

Compound Name

1-{2-ethyl-5-methylthieno[3,4-d]pyrimidin-4-yl}-N-[(4-methylphenyl)methyl]piperidine-4-carboxamide

IUPAC name

1-{2-ethyl-5-methylthieno[34-d]pyrimidin-4-yl}-N-[(4-methylphenyl)methyl]piperidine-4-carboxamide

SMILES

CCc1nc2csc(C)c2c(N(CC2)CCC2C(NCc2ccc(C)cc2)=O)n1

InChI

InChI=1S/C23H28N4OS/c1-4-20-25-19-14-29-16(3)21(19)22(26-20)27-11-9-18(10-12-27)23(28)24-13-17-7-5-15(2)6-8-17/h5-8,14,18H,4,9-13H2,1-3H3,(H,24,28)

InChI Key

HTTJBVSNLAMRLN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27638731

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.57

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.547

Distribution Coefficient, logD

2.711

Water Solubility, LogSw

-4.41

Polar Surface Area

48.332

Acid Dissociation Constant (pKa)

12.56

Base Dissociation Constant (pKb)

9.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

Z354-0054 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Others

References: we are preparing a list of scientific research reports with Z354-0054 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z354-0054?
Check Price and Availability of Z354-0054, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z354-0054 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z354-0054
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z354-0054
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z354-0054 available by request