Z354-0940 Screening compound: 1-{2-cyclobutyl-5-methylthieno[3,4-d]pyrimidin-4-yl}-N-(2-methylphenyl)piperidine-4-carboxamide

Z354-0940 Screening compound: 1-{2-cyclobutyl-5-methylthieno[3,4-d]pyrimidin-4-yl}-N-(2-methylphenyl)piperidine-4-carboxamide
Z354-0940 Screening compound: 1-{2-cyclobutyl-5-methylthieno[3,4-d]pyrimidin-4-yl}-N-(2-methylphenyl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound Z354-0940
1-{2-cyclobutyl-5-methylthieno[3,4-d]pyrimidin-4-yl}-N-(2-methylphenyl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z354-0940

Molecular Formula

C24H28N4OS (C24 H28 N4 OS)

Compound Name

1-{2-cyclobutyl-5-methylthieno[3,4-d]pyrimidin-4-yl}-N-(2-methylphenyl)piperidine-4-carboxamide

IUPAC name

1-{2-cyclobutyl-5-methylthieno[34-d]pyrimidin-4-yl}-N-(2-methylphenyl)piperidine-4-carboxamide

SMILES

Cc1c2c(N(CC3)CCC3C(Nc3c(C)cccc3)=O)nc(C3CCC3)nc2cs1

InChI

InChI=1S/C24H28N4OS/c1-15-6-3-4-9-19(15)26-24(29)18-10-12-28(13-11-18)23-21-16(2)30-14-20(21)25-22(27-23)17-7-5-8-17/h3-4,6,9,14,17-18H,5,7-8,10-13H2,1-2H3,(H,26,29)

InChI Key

QVKUNGDERJWGPS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27638810

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.58

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.775

Distribution Coefficient, logD

2.400

Water Solubility, LogSw

-4.59

Polar Surface Area

45.573

Acid Dissociation Constant (pKa)

11.84

Base Dissociation Constant (pKb)

9.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.80

Z354-0940 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with Z354-0940 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z354-0940?
Check Price and Availability of Z354-0940, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z354-0940 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z354-0940
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z354-0940
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z354-0940 available by request