Z376-0387 Screening compound: 1-(4-acetylphenyl)-3-{2-[3-(3-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]ethyl}urea

Z376-0387 Screening compound: 1-(4-acetylphenyl)-3-{2-[3-(3-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]ethyl}urea
Z376-0387 Screening compound: 1-(4-acetylphenyl)-3-{2-[3-(3-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]ethyl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound Z376-0387
1-(4-acetylphenyl)-3-{2-[3-(3-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]ethyl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z376-0387

Molecular Formula

C24H23N5O2 (C24 H23 N5 O2)

Compound Name

1-(4-acetylphenyl)-3-{2-[3-(3-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]ethyl}urea

IUPAC name

1-(4-acetylphenyl)-3-{2-[3-(3-methylphenyl)-3H-imidazo[45-b]pyridin-2-yl]ethyl}urea

SMILES

CC(c(cc1)ccc1NC(NCCc(n1-c2cc(C)ccc2)nc2c1nccc2)=O)=O

InChI

InChI=1S/C24H23N5O2/c1-16-5-3-6-20(15-16)29-22(28-21-7-4-13-25-23(21)29)12-14-26-24(31)27-19-10-8-18(9-11-19)17(2)30/h3-11,13,15H,12,14H2,1-2H3,(H2,26,27,31)

InChI Key

BTWYHMVDKVKERJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27638918

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.454

Distribution Coefficient, logD

3.453

Water Solubility, LogSw

-3.65

Polar Surface Area

69.087

Acid Dissociation Constant (pKa)

11.63

Base Dissociation Constant (pKb)

4.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

Z376-0387 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with Z376-0387 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z376-0387?
Check Price and Availability of Z376-0387, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z376-0387 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z376-0387
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z376-0387
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z376-0387 available by request