Z601-8187 Screening compound: 4-methyl-6-(morpholin-4-yl)-3H,4H-pyrido[2,3-b]pyrazin-3-one

Z601-8187 Screening compound: 4-methyl-6-(morpholin-4-yl)-3H,4H-pyrido[2,3-b]pyrazin-3-one
Z601-8187 Screening compound: 4-methyl-6-(morpholin-4-yl)-3H,4H-pyrido[2,3-b]pyrazin-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound Z601-8187
4-methyl-6-(morpholin-4-yl)-3H,4H-pyrido[2,3-b]pyrazin-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z601-8187

Molecular Formula

C12H14N4O2 (C12 H14 N4 O2)

Compound Name

4-methyl-6-(morpholin-4-yl)-3H,4H-pyrido[2,3-b]pyrazin-3-one

IUPAC name

4-methyl-6-(morpholin-4-yl)-3H4H-pyrido[23-b]pyrazin-3-one

SMILES

CN1c2nc(N3CCOCC3)ccc2N=CC1=O

InChI

InChI=1S/C12H14N4O2/c1-15-11(17)8-13-9-2-3-10(14-12(9)15)16-4-6-18-7-5-16/h2-3,8H,4-7H2,1H3

InChI Key

NCSGJMSSYGXATO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27639883

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

246.27

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.755

Distribution Coefficient, logD

0.755

Water Solubility, LogSw

-1.48

Polar Surface Area

45.411

Acid Dissociation Constant (pKa)

24.57

Base Dissociation Constant (pKb)

1.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

Z601-8187 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Fragments Library (11262 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Agro:
  • Agro
Structure:
  • Fragments
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with Z601-8187 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z601-8187?
Check Price and Availability of Z601-8187, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z601-8187 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z601-8187
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z601-8187
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z601-8187 available by request