Z606-8337 Screening compound: 1-{5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}-4-(propan-2-yl)piperazine

Z606-8337 Screening compound: 1-{5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}-4-(propan-2-yl)piperazine
Z606-8337 Screening compound: 1-{5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}-4-(propan-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound Z606-8337
1-{5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}-4-(propan-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z606-8337

Molecular Formula

C14H22N6 (C14 H22 N6)

Compound Name

1-{5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}-4-(propan-2-yl)piperazine

IUPAC name

1-{56-dimethyl-[124]triazolo[15-a]pyrimidin-7-yl}-4-(propan-2-yl)piperazine

SMILES

CC(C)N(CC1)CCN1c1c(C)c(C)nc2ncnn12

InChI

InChI=1S/C14H22N6/c1-10(2)18-5-7-19(8-6-18)13-11(3)12(4)17-14-15-9-16-20(13)14/h9-10H,5-8H2,1-4H3

InChI Key

MZMYTXBIKFOJNJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27640683

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

274.37

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.761

Distribution Coefficient, logD

0.019

Water Solubility, LogSw

-1.29

Polar Surface Area

38.439

Acid Dissociation Constant (pKa)

23.10

Base Dissociation Constant (pKb)

9.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

64.30

Z606-8337 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Fragments Library (11262 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Soluble Diversity Library (15920 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Structure:
  • Fragments
Targets:
  • Others
  • Proteases
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with Z606-8337 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z606-8337?
Check Price and Availability of Z606-8337, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z606-8337 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z606-8337
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z606-8337
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z606-8337 available by request